Quasi-continuous cotranslational compaction and folding of a multidomain protein
Most proteins start to fold cotranslationally as they come off the ribosome. So far, studies of cotranslational folding have focused mainly on small, single-domain proteins. Here, we have used Force Profile Analysis to study the cotranslational folding of Firefly Luciferase, a complex 550-residue protein composed of an...
Spyridoula Mitsikosta, Justin M. Westerfield, Fátima Pardo-Avila et al.
· Nature Communications · 0 citations