Author

Fei Yu

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Review Open access Sep 2026

Nanotherapeutic Strategies for MASLD: From Pathological Mechanisms to Targeted Delivery Systems

Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) is a progressive metabolic liver disorder driven by hepatic lipid overload, oxidative stress, mitochondrial dysfunction, innate immune activation, insulin resistance, gut–liver axis dysregulation, and liver fibrosis. These interconnected patholog...

Na Li, Dong-Qi Zhou, Fang-Hang Ye et al. · International Journal of Nan... · 0 citations

#gene editing Open access Oct 2026

Metabolic-epigenetic regulation of the HBV cccDNA reservoir: pathways underpinning viral persistence

Chronic hepatitis B virus (HBV) infection remains a global public health burden, and functional cure represents the primary goal of clinical management. The nuclear covalently closed circular DNA (cccDNA) minichromosome stably maintained in infected hepatocytes constitutes the major barrier to HBV cure. Clinically, f...

Qing Peng, Li-Yuan Hao, Sheng-Hao Li et al. · Frontiers in Microbiology · 0 citations