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Feng Jiang

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Open access Aug 2026

AI-driven dual-task prediction model for co-stratifying efficacy and toxicity in NSCLC immunotherapy

While effective against non-small cell lung cancer (NSCLC), PD-1 inhibitors can induce immune-related adverse events (irAEs), occurring in up to 15.2% of patients and potentially fatal. Currently, effective predictive biomarkers capable of simultaneously forecasting both irAEs and immune checkpoint inhibitor (ICI) resp...

Hanlin Ding, Yu-Ting Ren, Siqi Ding et al. · 0 citations
Open access Jul 2026

hsa_circ_0008758 Activates the MDM2/FOXO3a/PGK1 Pathway Through the miR-361-3p/SPIN1 Axis to Promote the Warburg Effect of Non-Small Cell Lung Cancer

Inhibiting circ_0008758 or elevating miR-361-3p resulted in decreased proliferation, migration, invasion, and Warburg effect in NSCLC cells, while promoting cell apoptosis, and circ_0008758 was found to enhance SPIN1 expression by acting as a sponge for miR-361-3p.

Lei Wei, Fei Xu, Lei Xiong et al. · 0 citations

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