Reversible Modulation of Glycan Recognition in C‐Type Lectins by Calcium/Lanthanide Exchange
C‐type lectins are Ca2+‐dependent glycan‐binding proteins involved in immune recognition and host–pathogen interactions. Previous structural studies suggested that lanthanide ions can replace Ca2+ while preserving protein structure, raising the possibility of exploiting paramagnetic lanthanides as NMR probes for studyi...
Pablo Valverde, Paola Oquist-Phillips, Ángeles Canales et al.
· ChemBioChem · 0 citations