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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

G. Balmus

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2 papers indexed here

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#gene editing Open access Oct 2026

Prime editing enables high-throughput identification and characterization of selective MutSβ inhibitors

This effort identified a novel series of MutSβ inhibitors that reduced (CAG)n expansion in a cell model and established several methods for systematically interrogating MMR, with demonstrated capacity to identify inhibitors of therapeutic value.

Yangwode Jing, Jun Yan, Denny Yang et al. · 0 citations
Open access Aug 2026

Targeting epigenetic regulators induces transcription-replication conflicts to overcome ATR inhibitor resistance

Abstract Many cancer cells exhibit elevated replication stress and are highly dependent on ataxia telangiectasia and Rad3-related (ATR) kinase activity to maintain genomic stability and survival. While ATR inhibitors (ATRi) have great promise as therapeutic agents, intrinsic or acquired resistance will likely be a sign...

Samah W. Awwad, Holly Barber, Josie Coulthard et al. · 0 citations

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