Author

G. Brixi

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#large language models Open access Sep 2026

Coevolutionary mining of prokaryotic non-coding elements with a genome language model

Microbial genomes encode non-coding RNAs (ncRNAs) and nucleic-acid-interacting proteins essential to biology and biotechnology. However, discovery of these systems remains protein-centric and based on similarity to known sequences. Here, we introduce Minerva, a framework for coevolutionary mining that uses genome langu...

David B. Li, G. Brixi, Alexandra S. Kim et al. · bioRxiv · 1 citation

Open access Sep 2026

Forecasting viral evolution from phylogenetic trees

Viral mutation forecasting plays a key role in pandemic preparedness by enabling researchers to anticipate novel variants and design proactive interventions. Evolutionary histories, represented as phylogenetic trees, offer key insights into the emergence of past and present strains, yet their role in predicting future...

I. Specht, Soyoon Park, Seyone Chithrananda et al. · bioRxiv · 0 citations