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Open access Sep 2026

Characterization of tri-culture alveolar-like organoids to study fibrotic lung diseases

Tri-culture alveolar-like organoids exhibited stimulus-specific responses in a 3D multicellular system, supporting their use for mechanistic studies of epithelial-mesenchymal crosstalk, environmental exposures, and therapeutic responses.

Tony J. F. Guo, Yi-Dan Meng, Seowon Kim et al. · 0 citations
Open access Jul 2026

Prevalence, detection, and trajectory of combined pulmonary fibrosis and emphysema.

BACKGROUND Combined pulmonary fibrosis and emphysema (CPFE) is an important phenotype in patients with fibrotic interstitial lung disease (ILD). RESEARCH QUESTIONS (1) What is the prevalence of CPFE? (2) What is the predictive performance of the CPFE Index and of physiological airflow obstruction for computed tomogra...

Y. Khor, Daniel-Costin Marinescu, H. Manganas et al. · 0 citations

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