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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

G. Hu

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3 papers indexed here

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Open access Sep 2026

Endoplasmic reticulum stress reduces caspofungin resistance in Cryptococcus neoformans

ABSTRACT Echinocandin antifungal drugs, such as caspofungin, inhibit β-1,3-glucan synthesis to impair cell wall formation. Caspofungin is effective in the clinic against Aspergillus and Candida species but ineffective against Cryptococcus neoformans, the fungus responsible for life-threatening meningoencephalitis in im...

Xian-Ya Qu, G. Hu, Christopher W. J. Lee et al. · 0 citations
Open access Aug 2026

Subunits of adaptor protein complex-1 make distinct contributions to the virulence of Cryptococcus neoformans

It is demonstrated that deficiencies in the AP-1 complex impair C. neoformans virulence, reveal distinct roles for individual subunits, and identify the complex as a potential target for therapeutic intervention in cryptococcosis.

Kabir Bhalla, Eddy Sánchez-León, Yu-Hsuan Huang et al. · 0 citations
Open access Aug 2026

The AP-1 adaptor complex is required for cell surface modifications and the survival of Cryptococcus neoformans in phagocytic cells

ABSTRACT The pathogenic yeast Cryptococcus neoformans causes life-threatening meningoencephalitis in individuals with compromised immune systems. The ability of the fungus to cause disease depends on key cell-surface features, such as a polysaccharide capsule that protects it from the mammalian immune system. However,...

Eddy Sánchez-León, Kabir Bhalla, Victoria French et al. · 1 citation

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