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Review Open access Oct 2026

From Engraftment to Vision: Defining Evidence of Functional Success in Retinal Cell Replacement Therapy

Retinal graft survival and post-treatment visual improvement do not, alone or together, demonstrate functional cell replacement. Apparent benefit may reflect material transfer, trophic rescue, residual host function or procedural and measurement effects. This critical narrative review uses a structured PubMed search co...

G. Panos, Theo Empeslidis, E. Chatzimichail et al. · 0 citations
Open access Sep 2026

Anatomical and Functional Outcomes of Repeat Vitrectomy Combined with Encircling Scleral Buckling for First Recurrent Rhegmatogenous Retinal Detachment After Primary Vitrectomy: A Retrospective Cohort Study

Descriptive break location findings identify inferior break-related recurrence as a candidate phenotype for future comparative evaluation, but the absence of a repeat PPV-only comparator precludes attribution of incremental benefit to the buckle.

G. Panos, Alex Stubbing-Moore, D. Kumudhan et al. · 0 citations
Editorial Open access Aug 2026

Clinical In Silico Studies in Drug Development and Therapy: Simplified Guidance for Authors, Reviewers and Editors

Clinical in silico studies are used in drug development and to assess therapies. 1 They include pharmacokinetic and pharmacodynamic analyses, dose and schedule selection, disease-progression models, evidence synthesis, virtual populations and clinical-trial simulations. By combining evidence from several sources, they...

G. Panos, F. Boeckler · 0 citations

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