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Genesis Vega Hormazabal

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#gene editing Open access Sep 2026

The longevity gene APOE2 enhances pericyte function and reduces lipid droplets.

Pericytes are critical for maintaining blood-brain barrier (BBB) integrity and have emerged as key contributors to Alzheimer's disease (AD) pathogenesis. Although the apolipoprotein E2 (APOE2) allele is associated with reduced AD risk and increased longevity, its impact on pericyte function is unclear. We measured peri...

R. Kadir, J. Bons, Genesis Vega Hormazabal et al. · 0 citations

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