With the rapidly expanding repertoire of literature in the life sciences, efficiently extracting and integrating critical biomedical information from texts has emerged as an urgent challenge. Fuelled by the development of lipidomics, lipids have garnered increasing attention for their roles as essential molecules that...
Le-Song Mo, Bo-Wen Li, Xiao-Wei Li et al.· Science Bulletin· 0 citations
Summary Background Abnormal birth weights are associated with adverse pregnancy outcomes and future metabolic consequences. We aimed to examine cord blood lipidomes from low, normal and high birth weight (LBW, NBW, HBW) infants to identify core lipid signatures associated with non-optimum birth weight, and to derive bi...
MPXV infection reprograms host lipid metabolism and exosome composition, with HIV co-infection amplifying inflammatory, metabolic, and trafficking disruptions and link systemic lipid dysregulation to exosome-mediated immunomodulation and identify potential targets for host-directed interventions.
Siqi Yong, Jiaying Zhang, He Tian et al.· i Medicina· 0 citations
A senescent-like MuSC population emerging in acute injury induced muscle regeneration is defined and definitive evidence to demonstrate the positive role of these cells in enhancing muscle repair via their robust secretory phenotypes and inter-cellular communicative capacity is provided.
Xing-Yuan Liu, Ying-Kun Zhang, Yang Li et al.· bioRxiv· 0 citations
These findings reveal a mechanistic role for PI4P in mediating activity-dependent, SNARE-driven fusion of AMPAR exocytic vesicles with the PM, which is necessary for both LTP and long-term memory.
Jing Xi, Shen Wang, Deng Pan et al.· bioRxiv· 0 citations
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