Zebrafish in the era of single-cell and spatial transcriptomics: a new paradigm for central nervous system drug discovery from natural products.
Natural products (NPs) represent a an important chemical source for CNS therapeutics for central nervous system (CNS) therapeutics, yet elucidating their complex, multitarget mechanisms remains a major challenge. Zebrafish have emerged as a powerful vertebrate model bridging the translational gap between in vitro assay...