Imidaclothiz (IMZ), a next-generation neonicotinoid pesticide, has garnered significant attention due to its detection in human samples. In this study, we investigated its toxicokinetics and biotransformation in rats following oral administration. IMZ was rapidly absorbed, reaching peak plasma concentration at 0.75 h...
Yi-Shuang Duan, Nian Xiong, Xiao-Ran Zhang et al.· Journal of Agricultural and...· 0 citations
The rapid expansion of chemical production and use has increased human exposure to environmental chemicals that can impact biological pathways relevant to mammary carcinogenesis. This trend creates an urgent need for scalable screening tools that can identify chemicals of potential concern before extensive animal testi...
Yu Qiu, Yi-Qu Wu, Fang Wan et al.· Environmental Pollution· 0 citations
This work established a suspected screening strategy based on segmental scanning and detected 33 SAOs and 21 TPs in serum samples, which included 9 newly-found TPs from the hydroxylation, sulfation or acetylation of SAOs.