Author

Guo-Guang Zhao

2 papers indexed here

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Review Open access Sep 2026

Focal Cortical Dysplasia Type II: Somatic Mutations, Molecular Mechanisms, and Integrative Multi‐Omics Framework

ABSTRACT Background Focal cortical dysplasia Type II (FCD II) is a major cause of drug‐resistant epilepsy in children. Somatic mosaic variants affecting the PI3K–AKT–mTOR pathway are implicated in a substantial proportion of cases. The links between genotype, cellular pathology, epileptogenic networks, and clinical out...

Ze-Sheng Li, Yi-He Wang, Jian-Wei Shi et al. · CNS Neuroscience & Therapeut... · 0 citations

Sep 2026

Joint impact of pathological burden and cognitive resilience on Alzheimer's disease risk.

The findings broaden the understanding that AD dementia is shaped jointly by pathological burden and cognitive resilience, and argue for therapeutic trial and prevention strategies that strengthen resilience alongside reducing pathology.

Zhi-Bo Wang, Shu-Heng Wang, Yu-Mei Liang et al. · Nature Medicine · 1 citation