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Gurman Kaur

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#gene editing Review Open access Oct 2026

From Pan-T-Cell Depletion to Selective Graft Engineering: Progress, Limitations, and Open Questions

This review traces that evolution, from CD34+ selection through αβ/CD19 depletion, naïve (CD45RA+) T-cell depletion, adoptive add-back, and gene-edited donor grafts, evaluated against current in vivo prophylaxis, principally post-transplant cyclophosphamide (PTCy).

Kirsty M. Sharplin, Sorur Moshgelgosha, Gurman Kaur · 0 citations

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