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Author

H. Arslan

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Open access Sep 2026

Melatonin Differentially Modulates Temozolomide Responses in Glioblastoma and Endothelial Cells: Associations with Global DNA Methylation and Cortistatin Levels

Glioblastoma (GBM) is the most aggressive primary brain tumor in adults and remains highly resistant to current therapeutic strategies. Temozolomide (TMZ) is a standard chemotherapeutic agent used in GBM treatment; however, intrinsic and acquired resistance limits its efficacy. This study investigated treatment-associa...

G. Gundogan, A. Yurttaş, Y. Oltulu et al. · 0 citations
Jul 2026

Carvacrol induces apoptosis, modulates oxidative stress, and promotes G0/G1 cell cycle arrest in colorectal cancer cells.

It is demonstrated that carvacrol effectively inhibits CRC growth while exerting limited effects on normal colon fibroblasts, which support the further investigation of carvacrol as a potential complementary therapeutic agent for CRC.

A. Abuaisha, H. Arslan, Emir Nekay et al. · 0 citations

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