Jul 2026· Molecular and Cellular Biochemistry· 0 citations· 31 references
Medicine
TL;DR
It is demonstrated that carvacrol effectively inhibits CRC growth while exerting limited effects on normal colon fibroblasts, which support the further investigation of carvacrol as a potential complementary therapeutic agent for CRC.
Preliminary mechanistic insights into the effects of 10-HDA on gastric cancer cells are provided, demonstrating that 10-HDA suppresses the malignant phenotype of gastric cancer cells by coordinated activation of apoptosis and cell cycle blockade.
Lei Huang, Tianxin Lin, Shou-Fu Jiang et al.· Nutrients· 0 citations
Collectively, emodin suppresses CRCSC characteristics in vitro by downregulating Wnt/β-catenin signaling and inducing AIF-associated caspase-independent apoptosis, highlighting its therapeutic potential against CRC.
M. Ahmadi, Hong Lae Kim, H. Jung· Biomolecules & Therapeutics· 0 citations
Narciclasine is a promising natural-product-derived lead compound for further preclinical evaluation in HELLS-associated CRC vulnerabilities and is associated with HELLS downregulation, DNA damage-associated signaling, and apoptosis in CRC cells.
Yoon-Mi Lee, Su-Min Han, G. Park et al.· Pharmaceuticals· 0 citations
It was revealed that BLA could reduce MCF-7 cell viability, adhesion, and migration while elevating intracellular ROS, autophagy, and apoptosis in an amount-dependent way and that BLA may be a natural anti-cancer agent to prevent BC metastasis.
Xinyuan Niu, Periyannan Velu, A. Vijayalakshmi· Journal of Pharmaceutical In...· 0 citations
Overall, BA exerted antiproliferative effects in MALME-3M cells accompanied by oxidative stress-associated cytotoxicity and changes in apoptosis-related markers, cell-cycle progression, migration-related features, and Wnt signaling-related markers.
Ş. Çelik, Hatice İlayhan Karahan, M. Soyöz et al.· Biological Trace Element Res...· 0 citations
Overall, EGCG and DOX exhibited synergistic interactions and multiple treatment-associated cellular and transcriptional responses in HeLa cells under the present in vitro conditions, which provide a basis for validation in additional cervical cancer models and at clinically relevant exposures.
Mehmet Emin Ayağ, M. Tuncer, Ş. Öztürk· Biomolecules· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.