Boric Acid Induces Oxidative Stress-Associated Cytotoxicity and Modulates Wnt Signaling in MALME-3M Cells.

Rosmarinic Acid Enhances Doxorubicin Activity in MDA-MB-231 Cells: Associations with Intracellular Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis

The RA + DOX combination showed synergistic cytotoxic activity in MDA-MB-231 cells, accompanied by increased intracellular oxidative activity, mitochondrial membrane depolarisation, apoptosis, cell-cycle perturbation, and changes in proliferation-related gene expression, which indicates associated cellular responses bu...

Comparative Effects of Metformin, Boric Acid, and Lithium Chloride on Oxidative Stress-Mediated Cytotoxicity in HepG2 Hepatocarcinoma Cells.

Antiproliferative Effects of Reynoutrin via Modulation of Oxidative Stress, Inflammation, and Apoptosis in Breast Cancer (MCF-7) and Prostate Cancer (PC-3) Cell Lines.

Tomentosin Potentiates Cisplatin-Induced Apoptosis and Modulates Proteostasis-Related Proteins in A549 Lung Cancer Cells

Findings indicate that tomentosin exerts antiproliferative and pro-apoptotic effects in A549 cells and that combined exposure with cisplatin is associated with a greater biological response under the investigated in vitro conditions.

Bortezomib induces ROS-dependent mitochondrial apoptosis and suppresses SKP2 signaling in cutaneous T-cell lymphoma cells

Cutaneous T-cell lymphomas (CTCL) are skin-homing T-cell malignancies characterized by recurrent disease, therapeutic resistance and limited durable treatment responses in advanced stages. Although the proteasome inhibitor bortezomib has demonstrated activity in CTCL, the molecular pathways associated with its an...

Bullatine A Attenuates Proliferation in Breast Cancer Cells by Apoptosis via PI3K/AKT/mTOR Signaling Pathway in Vitro and in Silico Analysis and Pharmacological Analysis

It was revealed that BLA could reduce MCF-7 cell viability, adhesion, and migration while elevating intracellular ROS, autophagy, and apoptosis in an amount-dependent way and that BLA may be a natural anti-cancer agent to prevent BC metastasis.