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It is shown that Cfap410a is a proximity partner of Cby and that they act cooperatively in the hierarchy of the TZ assembly program by bridging the CEP290 and MKS transition zone modules.
These findings uncover an active, centrosome-dependent, cell-autonomous mechanism for maintaining and repairing mature metazoan cilia in fully grown organs in adulthood and also provide a possible explanation for how deregulation of conserved ciliary base components could lead to progressive, late-onset cilia-related d...
This study provides updated genomic insights into circulating S. Typhi in Pakistan and proposes novel, computationally validated vaccine targets, laying a crucial foundation for subsequent experimental investigation.
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