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Review Open access Aug 2026

Efficacy and Safety of Mechanical Insufflation–Exsufflation in Invasively Ventilated Critically Ill Adults: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Mechanical insufflation–exsufflation (MI–E) is increasingly used in invasively ventilated adults in the intensive care unit (ICU), yet its therapeutic efficacy and safety remain uncertain due to inconsistent evidence.

Zhi-Qun Liu, Guiling Liao, H. Wen et al. · 1 citation

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