Sep 2026
Paeoniflorin attenuates experimental autoimmune encephalomyelitis in mice in association with enhanced Treg differentiation and activation of Raf/MEK1/2/ERK1/2/Egr-1 signaling.
Results indicate that PF treatment is associated with modulation of the Treg/Th17 balance in EAE mice and with changes in Raf/MEK1/2/ERK1/2/Egr-1 signaling in Jurkat cells, indicating a significant neuroprotective effect.
Xiao-Juan Zhang, Ying-Ying Song, Xinyan Han et al.
· Naunyn-Schmiedeberg's Archiv... · 0 citations