Thymoquinone alleviates DSS-induced colitis in mice by protecting the intestinal mucosal barrier through inhibition of the Notch signalling pathway.
OBJECTIVE To investigate the therapeutic effects and potential molecular mechanisms of the natural plant monomer thymoquinone (TQ) on colitis in mice. Particular attention was paid to protecting intestinal barrier integrity, apoptosis, and inflammatory responses. METHODS Colitis was induced in mice using 3% Dextran S...