Compound Kushen Injection Alleviates Experimental Colitis in Mice by Regulating Macrophage Polarization through TLR4/NF-κB Signaling.

Thymoquinone alleviates DSS-induced colitis in mice by protecting the intestinal mucosal barrier through inhibition of the Notch signalling pathway.

OBJECTIVE To investigate the therapeutic effects and potential molecular mechanisms of the natural plant monomer thymoquinone (TQ) on colitis in mice. Particular attention was paid to protecting intestinal barrier integrity, apoptosis, and inflammatory responses. METHODS Colitis was induced in mice using 3% Dextran S...

[Effects of Dendrobium huoshanense polysaccharide in inhibiting intestinal fibrosis in ulcerative colitis via macrophage IL-36α pathway].

Calming the inflammatory storm: 4-methylcatechol ameliorates DSS-induced colitis by suppressing the NLRP3 inflammasome signaling pathway

The natural polyphenol metabolite 4-methylcatechol (4-MC) has demonstrated anti-inflammatory and antioxidant properties. However, its effectiveness in ulcerative colitis (UC) and the molecular mechanisms involved are still poorly understood. This study aimed to evaluate the protective effects of 4-MC in a dextran s...

[Ethyl caffeate alleviates dextran sulfate sodium-induced colitis in mice by restoring intestinal epithelial tight junctions via activating the Wnt/β-Catenin pathway].

[Miao medicine Sidaxue regulates macrophage polarization and alleviates synovial inflammation in collagen-induced arthritis rats by inhibiting HIF-1α/PDK1-mediated glycolytic reprogramming].

[Effects of Qingzao Jiufei Decoction on bleomycin-induced pulmonary fibrosis via JAK1/STAT6 signaling pathway-mediated polarization of M2 macrophages].