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Haiping Liu

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Open access Sep 2026

Cdk1 heterozygosity triggers premeiotic endoreplication and unreduced sperm formation via the Cdk2/Ccne1-Fzr1a pathway in loach, a teleost.

Polyploidy represents a major driver of eukaryotic genome evolution. In vertebrates, premeiotic endoreplication is considered as an important route to polyploidization, yet the molecular basis governing this process remains elusive. Here, we reported that heterozygous mutation of cdk1 in the loach, Misgurnus anguillica...

Yun-Bang Zhang, Rong-Yun Li, Yi-Hui Mei et al. · 0 citations
Jul 2026

Integrated Analysis of Physiological, Histological, and Transcriptomic Responses to Transport Density in Schizothorax nukiangensis

Both gill and liver exhibited pronounced enrichment of lipid metabolism–related pathways—including steroid biosynthesis, fatty acid metabolism, glycerolipid metabolism, and fat digestion and absorption—accompanied by extensive upregulation of these genes, which are tightly associated with activation of the PPAR signali...

Jin-Li Wang, Yuting Duan, D. Gu et al. · 0 citations

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