Genomically similar viruses often differ in pathogenicity and host tropism due to specific mutations, and failure to distinguish them risks misdiagnosis and ineffective control. Molecular methods can differentiate such viruses but require laboratory settings and skilled personnel, while field-deployable immunological m...
Shu-Sen Ji, Li Ma, Jun-Jie Yang et al.· Talanta: The International J...· 0 citations
This work engineered a full-structural-protein virus-like particle co-assembled with PEDV S, M, N, and E proteins into uniform nanoscale particles, further formulated with a dual-adjuvant system of AS03 and CpG ODN and conferred robust protection against PEDV challenge in piglets.
Fei-Yang Jiang, Lian-Mei Bai, Yan-Yuan Zhang et al.· ACS Applied Materials and In...· 0 citations
The core pathogenic role of the LCN2‐MMP9‐ECM‐FAK axis in GC‐induced muscle atrophy is revealed, providing a promising novel therapeutic target for steroid myopathy.
Hongwei Shi, Xiaojing Hao, Yi Yan et al.· Advancement of science· 0 citations
A Thermally regulated, Oligonucleotide-mediated one-Pot System for CRISPR-Cas12a (TOPS-CRISPR), which employs a programmable inhibition strategy based on complementary RNA blockers with tunable length and binding sites, enabling efficient and reversible steric inhibition of the LbCas12a-crRNA ribonucleoprotein (RNP) co...
Shusen Ji, Bin Wang, Yi Yan et al.· Biosensors & bioelectronics· 0 citations
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