Engineering Piezo1‐Mediated Calcium Signalling for Enhanced Extracellular Vesicle Biogenesis and Cargo Loading
The use of the mechanosensitive ion channel Piezo1 as a robust regulator of EV biogenesis is exploited and mechanotransduction is identified as a key regulator of sEV biogenesis, underscoring the need for precise temporal control for the rational engineering of next-generation sEV therapeutics.
N. Saleh, Rozita Shafiq, A. P. Cicerone et al.
· Journal of Extracellular Bio... · 0 citations