These findings reveal that the RSV F antigen recognizes both the wild-type and AAS-mutated bispecific antibodies in a conformation-dependent manner, with binding preferentially observed for larger conformations.
Fanny C. Liu, Thais Pedrete, Andrew H. Beaven et al.· 0 citations
A streamlined Azo-enabled one-pot extraction strategy for high-sensitivity top-down analysis of PLN that reduces the required tissue input to 1 mg while preserving analytical performance and establishing a practical strategy for TDP of PLN proteoforms from biopsy-scale and other sample-limited myocardial specimens.
Isabella R. Clemmer, Holden T. Rogers, M. C. Wilson et al.· Journal of the American Soci...· 0 citations
The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post-translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)-based proteomics has emerged as an essential technique for elucidating this mo...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant et al.· Mass spectrometry reviews (P...· 1 citation
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