Development and validation of a novel rivaroxaban calibrator: A routine anti-Xa assay solution with high agreement with LC-MS/MS.
OBJECTIVES Therapeutic drug monitoring of rivaroxaban is essential for select patients, but anti-Xa assays can show discrepancies with the Liquid chromatography-tandem mass spectrometry (LC-MS/MS) reference method due to calibrator differences. This study aimed to develop and validate a novel rivaroxaban calibrator to...