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Hong-Ying Chen

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Open access Aug 2026

A Lipid Nanoparticle-Formulated GP5-mRNA Vaccine Induces PRRSV-Specific Humoral and Cellular Immune Responses in BALB/c Mice

Simple Summary Porcine reproductive and respiratory syndrome virus (PRRSV) is an important pathogen that causes severe economic losses in the swine industry. Current vaccines are useful but often provide limited protection against genetic diversity or newly emerging PRRSV strains. Therefore, new vaccine strategies are...

Jia-Qi Zhang, Jian Huo, Lan-Lan Zheng et al. · 0 citations
Sep 2026

A Single-Tube Dual-Gene RAA-PfAgo Assay for Simultaneous Detection and Identification of PEDV Field and Vaccine Strains.

Porcine epidemic diarrhea virus (PEDV) poses a significant threat to the swine industry, and distinguishing circulating field strains from vaccine strains under field conditions remains challenging. In this study, we established a one-tube visual detection platform based on recombinase‑aided amplification (RAA) and PfA...

Tao Wang, Jia-Qi Zhang, Hong-bo Cui et al. · 0 citations
#gene editing Open access Sep 2026

Construction and Immunogenicity of a Recombinant Pseudorabies Virus Expressing the Major Neutralizing Epitopes A and D of Transmissible Gastroenteritis Virus Spike Protein

A recombinant virus called rPRV-AD is built that carries key bits of the transmissible gastroenteritis virus (TGEV) spike protein that exhibited lower protective efficacy against TGEV than a commercial vaccine, while comparable protective observations were obtained against pseudorabies.

Li Zhao, Xiang-Shuo Tian, Tong Xu et al. · 0 citations

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