Author

Huang Huang

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Open access Aug 2026

Integrating single-cell and bulk RNA data to explore the prognostic significance of LIM domain family genes in colorectal cancer and unveil their immune landscape

It was revealed that cells with high LIM scores were predominantly fibroblasts, and Erlotinib, fulvestrant, EPZ5676, and AZD1208 were identified as potential therapeutic agents for patients in the low-LIMRS group, whereas vinblastine, docetaxel, paclitaxel, and vinorelbine may be more suitable for high-LIMRS group pati...

Xin-Yu Zhao, Yili Shao, Huang Huang et al. · Translational Oncology · 0 citations

Aug 2026

FGFR2 mediates the progression of colorectal cancer by promoting the expression of HIF-1α via the PI3K/AKT/mTOR pathway.

In vitro results of this study show that FGFR2 mediates HIF-1α and affects CRC cell proliferation, migration and invasion, which is consistent with the results of bioinformatics analysis.

Yi-Yang Hu, Liu-Xu Yao, Yuhong Li et al. · Tissue & Cell · 0 citations