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Author

Hugh Watkins

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Sep 2026

The Future of Genetic Therapy for Inherited Cardiomyopathy.

This Viewpoint explores the potential for genetic therapies to treat inherited cardiomyopathies at the intersection of unmet clinical need, patient appetite, and technological advances.

Rosemary B. Kirk, Alexander J. Sparrow, Hugh Watkins · 0 citations
#gene editing Review Sep 2026

Therapeutic upregulation of gene expression in inherited cardiomyopathies from current approaches to future directions

The mechanisms and current uses of gene upregulation strategies are reviewed and their advantages and limitations are critically evaluated as therapies for inherited cardiomyopathies.

Rosemary B. Kirk, C. Santiago, Hugh Watkins et al. · 0 citations
Open access Jul 2026

Unmasking Supervillin: SVIL haploinsufficiency causes hypertrophic cardiomyopathy by impairing mechanotransduction and cellular energetics

SVIL-associated cardiomyopathy is established as a mechanistically distinct form of HCM and drugs targeting mitochondrial bioenergetics may be a therapeutic strategy in patients with SVIL-associated cardiomyopathy.

Yifan J. Li, Y. Psaras, V. Steeples et al. · 0 citations

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