The Future of Genetic Therapy for Inherited Cardiomyopathy.
This Viewpoint explores the potential for genetic therapies to treat inherited cardiomyopathies at the intersection of unmet clinical need, patient appetite, and technological advances.
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This Viewpoint explores the potential for genetic therapies to treat inherited cardiomyopathies at the intersection of unmet clinical need, patient appetite, and technological advances.
The mechanisms and current uses of gene upregulation strategies are reviewed and their advantages and limitations are critically evaluated as therapies for inherited cardiomyopathies.
SVIL-associated cardiomyopathy is established as a mechanistically distinct form of HCM and drugs targeting mitochondrial bioenergetics may be a therapeutic strategy in patients with SVIL-associated cardiomyopathy.
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