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Open access Oct 2026

Inflammation- and metabolism-related transcriptional features in murine lupus nephritis: A single-cell kidney reanalysis

Highlights • Single-cell atlas of lupus nephritis kidneys before and after treatment.• Therapy remodeled interferon and immune-response programs in kidney immune cells.• Myeloid cells shifted from glycolytic inflammation to oxidative metabolism.• 67 genes shared by lupus nephritis and ccRCC map to IFN, HIF-1a and exhau...

Xue-Rong Li, Qiu-Shi Fang, Liang Luo et al. · 0 citations
Review Open access Sep 2026

HMGB1 functional plasticity in neurodegenerative diseases and its translational implications

High mobility group box 1 (HMGB1) is a chromatin-associated protein that can be redistributed and released during cellular stress, when it acts as an extracellular alarmin within the broader family of damage-associated molecular patterns (DAMPs). Its functions depend on subcellular localization, redox and post-translat...

Wei-Cai Cai, Ya-Qiao Yi, Rong Zeng et al. · 0 citations

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