A Novel Spectrophotometric Approach for the Determination of Vitamin C Using Thiosemicarbazone and Its Application to Pharmaceutical Preparations
A new spectrophotometric method has been developed for the determination of Vitamin C in aqueous solutions. The method is based on the oxidative coupling reaction of Vitamin C with a Thiosemicarbazone reagent in an acidic medium and in the presence of potassium periodate. This reaction yields a stable, water-soluble, d...