Population Pharmacokinetics and Extrapolation of NP-011 from Animal to Humans: A Novel Therapeutic Candidate Protein for Metabolic Dysfunction-Associated Steatohepatitis
Background/Objective: Metabolic dysfunction-associated steatohepatitis (MASH), an advanced stage of metabolic dysfunction-associated steatotic liver disease (MASLD), is characterized by progressive liver fibrosis and represents an important therapeutic target. NP-011 is a truncated recombinant human milk fat globule EG...