Dynamics of Orthoflavivirus Reproduction and Cytokine Responses in the A549ACE2 and HEK-293T Cells
The HEK-293T cells exhibited deficiency in the immune response and A549ACE2 cells demonstrated presence of the IFN-α, TNF-α, IL-6, IL-18, and anti-inflammatory IL-4 cytokines after infection, which depended on both the virus and the viral dose.