#protein folding
Sep 2026
“Sex-divergent responses to microglial depletion suggest distinct regulatory dependencies in the aged brain”
Microglia are essential for brain homeostasis, yet their roles in the aged brain remain poorly defined. Using microRNA (miRNA) profiling, cellular-resolution spatial transcriptomics, and bulk proteomics in 21-month-old mice, we characterize sex-dimorphic responses to microglial depletion via CSF1R inhibition (PLX5622 t...
Amila Beganovic, M. Flotho, Jin-Xiu Li et al.
· bioRxiv · 0 citations