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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Ikuro Abe

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Oct 2026

Structural and Mechanistic Basis of Bacterial 2-Methyl-ACC Synthases

Cyclopropane-containing amino acids are found in diverse natural products and contribute to their structural complexity and biological activity. However, the distribution of bacterial biosynthetic pathways that produce methylated cyclopropane amino acids and the structural basis of methyl-SAM recognition remain poorl...

Lyu Zhou, Takahiro Mori, Takuto Ohmura et al. · 0 citations
#protein folding Open access Aug 2026

Identification and structural basis of a Chloroflexus protein with homology to Bacillus quorum sensing-related prenyltransferase

The structural basis for peptide prenylation by a ComQ-family enzyme is established, providing insight into the evolution of peptide-based indole prenylation within the IPPS superfamily, and support the view that ComQ-family enzymes constitute a distinct functional branch specialized for peptide modification.

Takashi Matsui, Sumika Inoue, Shunsuke Yanagimoto et al. · 0 citations
#protein folding Aug 2026

A Repurposed S-Adenosyl-l-Methionine Synthetase Mediates Cytidyl-Cyclitol Natural Product Assembly.

Nucleoside natural products exhibit diverse chemical architectures and potent biological activities, yet the biosynthetic strategies that generate their structural diversity remain incompletely understood. Here, we elucidate the early stage biosynthetic pathway of the cytidyl-cyclitol natural product K-563 and its deri...

Zhong-Tian Yu, Wen-He Zhang, Richiro Ushimaru et al. · 0 citations

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