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Author

Ileana Licona-Limón

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Open access Sep 2026

Non-Clinical Evaluation of the Anti-PD-1 Antibody UDIZ-007

UDIZ-007 demonstrated robust anti-tumor activity, favorable PK and safety profiles, as well as selective binding to PD-1-expressing tissues, supporting its clinical development as a potential cancer immunotherapy.

Gregorio de Jesús Carballo Uicab, Keyla María Gómez Castellano, Frida Daniela Ramírez Villedas et al. · 0 citations
Aug 2026

TIF1γ regulates stability of regulatory T cells during inflammation

It is shown that TIF1γ-deficient Treg cells lose Foxp3 expression and acquire effector phenotypes in a cell-intrinsic manner upon inflammatory challenge, and TIF1γ is identified as a critical regulator of Treg cell stability that restrains β-catenin–TCF7 signaling.

Eugenio Contreras-Castillo, Jesús Daniel Zambrano-Romero, H. N. Núñez-Martínez et al. · 1 citation

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