Irfan Cinar

In Vitro Investigation of the Antiproliferative Potential of the Achyranthes aspera Dichloromethane (DCM) Extract in SH-SY5Y Neuroblastoma Cells

Neuroblastoma is the most common extracranial solid tumor of childhood and arises from the sympathetic nervous system. Even with intensive, multimodal treatment, resistance, relapse, and treatment-related toxicity remain major problems in high-risk cases. Here we examined how the dichloromethane (DCM) extract of Achyra...

Protective effects of Aronia melanocarpa seed oil against doxorubicin-induced cardiotoxicity in H9c2 cells: insights from apoptosis-related mRNA expression and molecular docking analyses

Purpose: This study aimed to investigate the protective effects of Aronia melanocarpa (chokeberry) seed oil (ASO) against doxorubicin (DOX)-induced cardiotoxicity in H9c2 cells by evaluating apoptosis-related mRNA expression and assessing the potential interactions of ASO-derived fatty acids with apoptosis-related prot...

Antiproliferative Effects of Reynoutrin via Modulation of Oxidative Stress, Inflammation, and Apoptosis in Breast Cancer (MCF-7) and Prostate Cancer (PC-3) Cell Lines.