Author

J. Cooper-Knock

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Open access Aug 2026

Pathology-defined cell states reveal reproducible transcriptomic signatures across ALS cortical single-nucleus RNA-seq studies

It is demonstrated that pathology-defined cell states provide a more reproducible framework for studying ALS transcriptomic alterations than conventional case-control comparisons and an interactive browser is provided to facilitate exploration and comparison of ALS snRNA-seq datasets.

C. V. van Dijk, Sam Bonsall, A. Giani et al. · bioRxiv · 0 citations

Open access Jul 2026

Circulating protein profiling identifies prognostic biomarkers in amyotrophic lateral Sclerosis

The utility of multiple proteins reflecting diverse biological pathways in refining survival stratification is indicates the utility of multiple proteins reflecting diverse biological pathways in refining survival stratification and highlights systemic factors in ALS progression.

H. Klimovski, M. Weinreich, A. Strange et al. · medRxiv · 0 citations

Open access Jul 2026

A proteomic signature for prognostic stratification in amyotrophic lateral sclerosis

This work indicates the utility of multiple proteins reflecting diverse biological pathways in refining survival stratification and highlights systemic factors in ALS progression, highlighting their potential role in measuring disease progression.

D. Lester, P. Piazza, E. Dellar et al. · medRxiv · 0 citations