Label-Free and Strain-Resolved Characterization of AI-2 Associated Quorum Sensing Functional Phenotypes in Bacterial Isolates Using Single-Cell Raman Spectroscopy and Deep Learning
We evaluated the relationship between Raman spectral profiles obtained by single-cell Raman spectroscopy (SCRS) and autoinducer-2 (AI-2)-associated quorum sensing (QS) functional phenotypes using experimentally measured relative BB170 reporter responses as functional reference values. Based on this relationship, this...