Schizophrenia frequently follows a chronic relapsing-remitting course, comprising alternating episodes with and without psychotic symptoms (hereafter: psychosis and psychotic remission). One potential neurobiological correlate of this course is aberrant dopamine synthesis and storage (DSS) in the striatum, which can be...
Julia Schulz, M. Thalhammer, Moritz Bonhoeffer et al.· medRxiv· 0 citations
Mental health is fragile and disorders are highly prevalent arising from complex interactions between genetic, developmental, psychological, social and environmental factors. The key mechanisms underlying resilience, vulnerability factors, brain repair systems, and recovery remain poorly understood, hindering the devel...
S. Safaiyan, M. Schmidt, Annemarie Zimprich et al.· European Archives of Psychia...· 0 citations
Abstract Background and Hypothesis Schizophrenia spectrum disorders are typically described using positive and negative symptoms, yet standard diagnostic systems may not reflect the full range of how individuals experience the disorder. We hypothesized that synthesizing first-person accounts would yield a broader, clin...
S. F. Aprile, Alessandro Rodolico, Djordje Basic et al.· Schizophrenia bulletin· 0 citations
Psychiatric syndromes can be caused by underlying autoimmune encephalitis (AE). This represents a diagnostic challenge at the interface of psychiatry and neurology. While AE mostly manifests with a combined, complex neuropsychiatric syndrome, some patients with AE may (initially) present with predominant or isolated ps...
D. Endres, K. von Zedtwitz, Ludger Tebartz van Elst et al.· Molecular Psychiatry· 0 citations
We report a diagnostically challenging case of treatment-resistant depression (TRD) in a 52-year-old woman with multiple factors potentially increasing susceptibility to central nervous system (CNS) adverse effects, including global cortical atrophy, concomitant lithium and antipsychotic treatment, and ongoing programm...
E. Berthold, Meltem Baskonus, Joan Koti et al.· Journal of ECT· 0 citations
Clinicians should be aware of earlier attainment of substantial response of hostility and excitement, then positive symptoms, before substantial reductions in other domains, as improvement in these domains lags behind.
S. Leucht, Mathias Harrer, Susan Illing et al.· Lancet psychiatry· 2 citations
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