Potent reaction hijacking inhibitors of Plasmodium falciparum asparagine tRNA synthetase
ABSTRACT Malaria remains one of the major threats to human health. Breakthrough drugs with high potency and low resistance risk are needed to combat the ever-increasing resistance to currently deployed antimalarials. Here, we explore a series of 4-aminoquinazoline-based sulfonamides (4AQS), with a synthetically accessi...
Xi Ye, Lisl Y. Esherick, Nutpakal Ketprasit et al.
· mBio · 0 citations