Author

Jennifer Porat

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Open access Sep 2026

Unbiased, systematic surfaceome profiling of Acute Leukemia to identify novel immunotherapy targets

An unbiased atlas of the whole cell and surface proteomes of 25 commonly used leukemic cell lines, encompassing both lymphoid and myeloid lineages, and a variety of driver mutations, is presented, creating a resource for understanding these widely used models.

Benson M. George, Anna Rodríguez-Pöhnlein, D. DeCastro et al. · bioRxiv · 0 citations

2026

Use of tRNA-Mediated Suppression to Assess RNA Chaperone Function.

TRNA-mediated suppression can be a useful assay for the investigation of various proteins hypothesized to promote tRNA folding through RNA chaperone-related activities.

Jennifer Porat, M. Talebi, Alita M. Gideon et al. · Methods in molecular biology · 0 citations

2026

Analysis of tRNA Aminoacylation by Northern Blotting and Multiplex Small RNA-Seq.

Quantification of tRNA aminoacylation has been used to demonstrate RNA chaperone activity for RNA-binding proteins that promote tRNA folding to increase the fraction of aminoacylated tRNAs, underscoring the utility of this assay in interrogating RNA chaperone-assisted tRNA folding and function.

Jennifer Porat, Christopher P. Watkins, Mark A. Bayfield · Methods in molecular biology · 0 citations