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Author

Jeong Ho Hwang

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Open access Aug 2026

ε-Viniferin Attenuates LPS-Induced Inflammatory Activation in Canine Macrophages by Regulating NF-κB and MAPK Pathways

Chronic inflammation is a key pathogenic factor contributing to multiple canine diseases, including dermatitis, arthritis, and enteritis. This study investigated the anti-inflammatory effects of ε-viniferin, a resveratrol dimer, in lipopolysaccharide (LPS)-stimulated DH82 canine macrophages. The anti-inflammatory effec...

Minseo Cho, Ji-Su Lee, Hyunsoo Jang et al. · 0 citations
#gene editing Review Open access Sep 2026

Beyond immune rejection: integrative genetic engineering strategies for overcoming coagulopathy in xenotransplantation.

The four-decade evolution of genetically engineered (GE) pigs from the first α-1,3-galactosyltransferase knockout in 2003 to today's 10-gene and 69-edit donors has progressively dismantled the immunologic barriers to xenotransplantation. Hyperacute and acute humoral rejection have been largely overcome through triple k...

Jeong Ho Hwang · 0 citations

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