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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Jia-Jia Li

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3 papers indexed here

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Open access Sep 2026

High‐throughput identification of carboxylate‐free ligands for the E3 ligase Kelch domain‐containing protein 2

It is demonstrated that KLHDC2 can accommodate non-carboxylate scaffolds and expands the chemical space for developing KLHDC2-based targeted protein degradation strategies and expands the chemical space for developing KLHDC2-based targeted protein degradation strategies.

Yao Chen, Rui-Chen Gao, Jia-Jia Li et al. · 0 citations
#protein folding Open access Sep 2026

Consensus design and in silico screening of GH42 β-galactosidase for enhanced catalytic hydrolysis of whey lactose.

This study addresses a major bottleneck in dairy waste management by engineering a highly efficient, thermophilic enzyme for lactose hydrolysis, transforming the cheese manufacturing by-product whey into a high-value resource. While traditional glycoside hydrolase family 2 (GH2) enzymes suffer from poor industrial ther...

Si-Meng Ding, Jia-Jia Li, Jia-Hui Li et al. · 0 citations
Review Open access Sep 2026

Monovalent Nondegrading Molecular Glues: An Updated Overview of Emerging Mechanisms and Therapeutic Development

The ndMG modality represents a highly versatile strategy to unlock the undruggable proteome and is systematically highlighted to highlight their evolving capabilities to modulate oncogenic networks, intervene with immune activity, rectify metabolic signaling, control neurodegenerative trafficking and stress networks, a...

Lin-Feng Li, Jia-Jia Li, Li Yang et al. · 0 citations

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