Open access
Sep 2026
Reassessing the contribution of the histone H3 tail to KRAB–DNMT3L-mediated epigenetic silencing
It is suggested that the engineered H3 tail does not confer a general functional advantage within the KRAB–DNMT3L–dCas9 architecture under the conditions tested.
Ming-Lei Song, Jia-Jun Lei, Jian-Kang Zhu
· bioRxiv · 0 citations