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Multimodal AI and single-cell transcriptomics integrate to construct a histopathological prognostic model for bladder cancer, revealing the RTN3-glycolysis axis in chemoresistance
The findings establish the RTN3/JAK2/STAT3/glycolytic metabolic reprogramming axis as a critical mechanism of gemcitabine resistance, highlighting RTN3 as a promising therapeutic target for overcoming chemoresistance in bladder cancer.
Jianpi Qingre Qushi Formula attenuates acute gouty arthritis through modulation of the Ras/Raf/MEK/ERK signaling pathway.
It is suggested that JQR exerted therapeutic effects on AGA via the coordinated regulation of multiple components and targets through the Ras/Raf/MEK/ERK signaling pathway.