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Jiaqi Chen

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Open access Oct 2026

Cryptotanshinone Alleviates Cardiac Hypertrophy Through SIRT3-Mediated Epigenetic Regulation and Mitochondrial Dynamics

Cryptotanshinone (CTS), a bioactive diterpenoid extracted from Salvia miltiorrhiza Bunge, has long been recognized as a traditional Chinese herbal compound. This study reveals that CTS exerts potent anti-hypertrophic effects against angiotensin II (Ang II)-induced cardiac hypertrophy by targeting Sirtuin 3 (SIRT3)-medi...

Jian-Ming Xing, Peng Ji, Xin-Tong Gu et al. · 0 citations
#gene editing Review Open access Aug 2026

Applications of DNA Hydrogels in Osteoporotic Bone Defects

Pure and hybrid DNA hydrogels are proposed as novel therapeutic platforms to restore the dynamic balance between bone resorption and formation, thereby enhancing osteogenesis and facilitating bone regeneration and remodeling under osteoporotic conditions.

Jiaqi Chen, Hui-Yu Jia, Xin-Yue Zhang et al. · 0 citations

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