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Author

Jiang Lei

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Jul 2026

HNRNPF-driven retention of exon 14 in HIF1A pre-mRNA promotes breast cancer metastasis.

The HNRNPF/HIF1A-L/CXCR4/AKT axis as a central regulatory circuit controlling breast cancer metastasis is elucidated and it is suggested that correcting the aberrant splicing of HIF1A may represent a novel therapeutic strategy for cancer.

Mengzhen Huang, Jiang Lei, Wei Wu et al. · 0 citations